Palma begins to lose patience with the Pizzofalcone team, frustrated by the absence of concrete evidence and a network of still uncertain suspects. Meanwhile Lojacono confronts his lawyer, bringing to light personal difficulties, financial problems and the weight of a past that continues to haunt him.

The story of Sandra continues, a restaurateur in Miami, chosen to cook at a White House event for Barack Obama. Between initial disbelief and rigorous security checks, the experience becomes a source of great pride for her. The story also highlights the value of friendship and the importance of reinventing oneself in life.

Barbara avoids a meeting to take refuge in music, while the rest of the group confronts insecurities. A breathing crisis of little Chiara brings past fears back to light, but also the strength of mutual support. Meanwhile, among colleagues, the organization of an innovative concert takes shape.

The documentary follows journalist Annalena Benini on a journey through Italy discovering writers in the places that shaped them. The first stop is Naples, told through Valeria Parrella: an intense and complex city, where landscape, memory and daily life intertwine with literature and the identity of authors.

Torre and Piccolo arrest Alfredo Brachetti, suspected in the murder of Flora Torrielli. He denies everything and presents an alibi, but the agents remain suspicious and look for connections with other characters.

Lojacono and Romano interrogate Senatore, trying to verify the solidity of his alibi, while the investigation is practically at a standstill, with little to go on. As Lojacono is making his morning coffee, he gets a disturbing phone call from his ex-wife, Sonia.

The story of Sandra continues, a Tuscan chef who emigrated to the United States, who established herself in Miami with authentic Tuscan cuisine. Thanks to her continuous ties with Italy, she keeps her roots alive, even cooking for Barack Obama.

Matteo gets home and walks in on his uncle and Daniele, the neighbor. After Daniele leaves, Matteo talks to his uncle about his personal problems, wondering why he is behaving so badly.

During a visit to the CERN Control Center, one witnesses scientific research activity and ultra-high energy particle collisions. The account highlights the enthusiasm for discoveries, such as that of the Higgs boson, and the idea that the Universe is still largely unknown.

Camilla encourages Renzo, telling him that he will make an excellent impression with Roberta's parents, who seem very demanding, and confirms her confidence in the quality of the project he will present. Gaetano and Roberta also face doubts and small insecurities, showing the need to receive mutual reassurances.

A quiet evening among friends at Senatore's house is interrupted by the sudden arrival of the police. Inspector Giuseppe Lojacono continues the investigation into Lara's mysterious life: during the interrogation of her employer, contradictions and details about the woman's past emerge.

During an important evening at the Washington, D.C. restaurant where Sandra was the dining room manager, the usual chef didn't show, and Sandra found herself having to manage the kitchen as well. She had no experience there, and so it was somewhat of a disaster. The episode pushed her to learn, however: Thanks to the help of an expert cook, she began an apprenticeship, acquired skills, and started building a career bringing Italian cuisine to the United States.

Rosario claims he no longer worries about the consequences of his actions, because he will have to leave Milan anyway. Meanwhile, Domenico and Matteo clash harshly, calling their friendship into question amid accusations and betrayals. Sara is forced to confront a difficult reality, understanding that she must grow up quickly and put her emotional strength to the test.

Fabiola Gianotti's story combines professional growth and creative vision: from her beginnings in international protocol to a meeting with Barack Obama, to designing a space conceived to connect people and ideas, with an ironic ending related to the Higgs Boson.

After the match, Renzo, Camilla, and Gaetano try to encourage sportsmanship between Livietta and Nino. Gaetano introduces Roberta to Renzo, alluding to a possible collaboration between Roberta's parents and Renzo. The tension is palpable.