Matarazzo and Calagiuri hit a dead end in their first encounter at the University of Bari. Imma finally gets to consult the files associated with Bruno's disappearance fifteen years prior. Diana asks her for a favor she shouldn't have.

Michele has a rough time of it in Master Simone's workshop. It's clear, however, that he has talent. A Knight of Malta comes into the workshop to have a look.

When Luigi finds out he could actually have had some water before his CT scan, he is totally demoralized. He talks about the different kinds of patients to be found in any hospital.

Giuseppe, Cloe, and Nina have a relaxing moment together at home, but then a letter arrives for Giuseppe that challenges the lighthearted atmosphere they had created.

On the last day of school, Manzi goes to say goodbye to his pupils, who have taken the exam for their elementary school diplomas. He has written each of them a letter about how far they have come together and urging them never to give up. Outside the school, the principal wonders who all those people are, coming towards the school.

Camilla has to go down to the Carabinieri (police) headquarters. She tries to call Gaetano, to no avail. At the police station, she runs into the administrator of Dora's villa.

Nora manages to talk to Roberto for a moment to make sure he goes ahead with the divorce. She meets some potential new clients. Ugo is oblivious to these events and is busy buying flowers for Nora.

Some years have passed, and Michele's widowed mother has had some difficult decisions to make regarding her children. One of these is to send 12-year-old Michele to Milan to be an apprentice at the workshop of the well-known artist, Simone Peterzano. Michele has no desire to leave home and family.

Luigi spends the night tossing and turning. In the morning, a nurse comes to get him for the CT scan, but then he has to wait and wait.

Nina goes back home to get some of her things and finds Cloe. She doesn't hide her resentment, but the two women end up having a conversation. Elena is clearly stufa (fed up) with Giuseppe never having time for her and she takes action.

Manzi goes before the Board of Education. Ida finds some letters in Alberto's coat pocket. Manzi explains to the board members why he finds it impossible to give his pupils grades.

It's a difficult moment for Camilla, and there are tensions at home, which Livietta perceives quite well. Camilla talks to Detective Berardi about Dora's death.

After a night of intimacy, Ugo and Nora seem to have differing ideas about what it meant. Meanwhile, Iside and Dino are already basking in what they think is the aftermath.

Caravaggio is a TV mini-series based on the life of the Italian painter Michelangelo Merisi da Caravaggio. It opens in 1577 when the painter was 5 years old. The plague had just hit and people who were still alive were burning their household possessions.

Father Costa just wants to be left alone and chases Friar Marcello away. Luigi finally has his catheter and drainage removed.