Penelope gets some news she shares with Valentina. Imma is upset about Calogiuri's leaving, but throws herself into her work, confronting Bruno's son about his project in Vallone della Femmina.

Dottoressa Piras and Lojacono continue their conversation in the car in front of Lojacono's building. They address some serious topics that have nothing to do with the case they have just solved.

Amed predicts Luigi's future, and Luigi has some visions. This segment reveals the meaning of the title of the show.

Roberto is worried about how Ugo is acting. Manrico is trying to get Melody to go out with him. The bride-to-be shows up at the workshop with her girlfriends who want to plan a bachelorette party for her.

Young Michele thus enters into the service of Cardinal Francesco Maria del Monte, man of culture and art connoisseur. All he has to do is what he does best: paint.

Giuseppe's health is failing, but he won't accept Arcangelo and Nina's advice to get some rest. He seems to be well aware of his true condition and writes a letter to his loved ones. Elena brings Antonio home.

Camilla might have had a good hunch, but she is still in trouble up to her neck. Fortunately, she has a lot of support from her husband, her students, and her friend the cop.

Imma can't help herself and goes to the office. Diana gives her some important information to mull over. The young people are having a little party for Calogiuri who is leaving for his exam in Rome the next day.

After a long work day, everyone on the team goes home to a different situation, and it isn't always a happy one.

Amed is obsessed with the idea of eating the right kind of food to fight cancer, but he goes a little too far.

Nora is back, and as an excuse for keeping her distance, she uses the ruse Melody planned to employ with Giampi. But all this has to go on the back burner because there are new potential clients waiting downstairs.

Word seems to be getting around that Merisi is a very talented painter. In bed with malaria, Michele himself is the last one to hear about it.

Giuseppe goes to see Giorgio to see if he has the power to save the hospital from the new "reforms," but Giorgio has other priorities and rebuffs him.

Camilla has to leave the school without being seen by the two men who are following her. In discussing the case with Berardi, she realizes there is only one person who can help exonerate her so the two of them pay this person a visit.

Imma is taking a vacation day, but is she really capable of that? She goes hiking with Pietro but he slowly realizes she has ulterior motives. By chance, they meet up with Ettore Rossetti, the person who originally found the dead body of Domenico Bruno.