During a visit to the CERN Control Center, one witnesses scientific research activity and ultra-high energy particle collisions. The account highlights the enthusiasm for discoveries, such as that of the Higgs boson, and the idea that the Universe is still largely unknown.

Matteo gets home and walks in on his uncle and Daniele, the neighbor. After Daniele leaves, Matteo talks to his uncle about his personal problems, wondering why he is behaving so badly.

The story of Sandra continues, a Tuscan chef who emigrated to the United States, who established herself in Miami with authentic Tuscan cuisine. Thanks to her continuous ties with Italy, she keeps her roots alive, even cooking for Barack Obama.

Lojacono and Romano interrogate Senatore, trying to verify the solidity of his alibi, while the investigation is practically at a standstill, with little to go on. As Lojacono is making his morning coffee, he gets a disturbing phone call from his ex-wife, Sonia.

Torre and Piccolo arrest Alfredo Brachetti, suspected in the murder of Flora Torrielli. He denies everything and presents an alibi, but the agents remain suspicious and look for connections with other characters.

The documentary follows journalist Annalena Benini on a journey through Italy discovering writers in the places that shaped them. The first stop is Naples, told through Valeria Parrella: an intense and complex city, where landscape, memory and daily life intertwine with literature and the identity of authors.

Barbara avoids a meeting to take refuge in music, while the rest of the group confronts insecurities. A breathing crisis of little Chiara brings past fears back to light, but also the strength of mutual support. Meanwhile, among colleagues, the organization of an innovative concert takes shape.

The story of Sandra continues, a restaurateur in Miami, chosen to cook at a White House event for Barack Obama. Between initial disbelief and rigorous security checks, the experience becomes a source of great pride for her. The story also highlights the value of friendship and the importance of reinventing oneself in life.

Palma begins to lose patience with the Pizzofalcone team, frustrated by the absence of concrete evidence and a network of still uncertain suspects. Meanwhile Lojacono confronts his lawyer, bringing to light personal difficulties, financial problems and the weight of a past that continues to haunt him.

Livietta is using a bit of blackmail on her parents to get them to buy her some low-waisted pants. But Camilla and Renzo have their own problems. Renzo has to go to dinner with Roberta's parents, and Camilla gets an urgent phone call from Anna.

Valeria Parrella recounts her deep and complex bond with Naples, a city that is all about language, identity, and memory. Through Almarina, a Naples that is 'wonderful and terrible' emerges, but also a place of freedom, growth, and hope.

Irene is not so sure Marioni's car crash was really an accident, and the two talk frankly. Meanwhile, Robbo's sister Chiara has an asthma attack, and Robbo calls their father.

Sandra now lives in the Blue Ridge Mountains, in North Carolina. She is still working and loves it. She and Marika discuss some Italian expressions about the value of work and about how their friendship has lasted all these years.

An apparently insignificant detail on the onesie the baby was wearing when found by the dumpster leads Laura to question a version of events related to Lara's death. She and Lojacono go to question Lara's former employers once again.

Gaetano and Torre get called to the scene of another murder. Suspecting that the body is that of Quantunque, Gaetano calls Camilla, who has gone to Anna's restaurant to meet someone identifying himself as Quantunque. Anna turns out the lights at the restaurant and Gaetano turns on the siren of the squad car.