Giuseppe and Giorgio are dressed to go out on the town. They get temporarily sidelined by a kid trying to break into a house, who then falls. They go to a nightspot where there is a performer Giorgio has his eye on.

The evening Giorgio planned to spend with Cloe doesn't turn out as he had hoped. The next day at the hospital, on their first day of work, Giorgio and Giuseppe get to know Sister Helga who rules with an iron fist.

Giuseppe walks through the market and witnesses a scene whereby a carabiniere policeman chases down a kid who was trying to steal some food. The kid is one Giuseppe has seen before.

Giuseppe's passion for his work puts his patients' well-being ahead of following the rules and getting chastised by his superiors. Giorgio is much more easygoing and as soon as the shift is over, is ready to have fun.

Giuseppe stays late at work, which he is not allowed to do, and he gets an unusual visitor.

Moscati continues to disobey the rules of the hospital. Nobody can deny, however, that he is having some success with his methods.

Giorgio goes to see Cloe perform again, while Giuseppe takes Elena to a place that isn't easy to reach. The two friends are clearly in love.

In 1906 Vesuvius erupted, its worst eruption of the entire 20th century. Torre del Greco, a town near Vesuvius, was particularly affected. Buildings collapsed, sick people were trapped inside the hospitals, and Giuseppe and Giorgio rushed there to help out.

Moscati risks his life to save some of the patients from the hospital. It took courage and patience.

Both Giuseppe and Giorgio take the exam for the available position. They each have to diagnose a patient and the examination board isn't kind to either of them.

Giorgio goes to see Cloe perform, but afterwards, he makes an important decision. Giuseppe finally finds Aniello, who is not doing well at all.

Moscati can't find Aniello in the hospital and discovers he had run off. Moscati goes out looking for him.

Moscati discovers what Aniello died of and feels profoundly aggrieved and powerless. He seems to have doubts about his role as a doctor.

Sister Helga and Moscati give the patient a bath and talk about how medicine is nothing without love. Moscati has some unorthodox teaching methods, as well as some novel "therapy" for his patients.

Giorgio is getting settled in his new office and gets an unexpected and unwelcome visitor. Giuseppe has a big evening ahead of him with Elena and her father, but he gets some news he has to take care of and is delayed.