The investigation into Lara's death continues, while the police conclude the interrogation of the suspect. Meanwhile Aragona, in order to go out with Irina, promises her that he will find the culprit.

Rosario and his mother share a secret and touching moment in the school that the boy attends, between music and complicity. At Matteo's house, instead, tensions emerge between uncle and nephew, fueled by emotional conflicts and misunderstandings.

Camilla needs to speak to Anna and phones her, only to find out that Anna had just forced the briefcase open at Quantuque's place. Meanwhile, the investigators interrogate a witness who points to a possible suspect.

The police interrogate Cuocolo after the arrest and he tells of having met Lara on the Mergellina waterfront and of having had a casual relationship with her. However, he denies being the father of the child and claims to have an alibi for the night of the murder, suggesting that the culprit could be someone in love with her who was not reciprocated.

Rosario finally meets his mother during a visit. The two speak with affection, but also with a certain embarrassment about Antonia's difficult past, who however tells him she is feeling better and has reduced her medication. The woman then tries to learn more about her son's life, asking him about school and his friends. Meanwhile, Barbara is scolded by her mother because she is always glued to her phone.

Gaetano and Roberta argue heatedly about the wedding preparations and family responsibilities; the argument angers Roberta, who decides to leave. Meanwhile, Camilla asks Gaetano for help and, thanks to a photograph, a young man is connected to the woman found murdered. For this reason, Gaetano wants to speak with Anna to get more information and deepen the investigation.

Lojacono pursues and arrests Donato Cuocolo. After attempting to flee and threatening the officers with a brick, he is stopped by Alex Di Nardo. At the police station, the investigators put him under pressure: he risks many years in prison, but he can face a lighter charge if he cooperates.

Marioni is forced to give up conducting the concert due to his injury, while Rosario receives an affectionate visit from his mother, between tenderness and a touch of embarrassment. In a record shop, unexpected confidences emerge and, once again, between music and complicity, the young people confront love and friendship.

Camilla finds herself involved in the difficult situation of one of her former students, obsessed with Quantunque, who has mysteriously disappeared and whom she wants to help at any cost. Between enigmatic messages and a photograph that has resurfaced from the past, the investigations proceed amid suspicions and uncertainties, without yet a real breakthrough.

While Romano talks with the doctor, he meets Giorgia at the hospital, who is there to assist her hospitalized mother. Meanwhile, at the police station, new clues emerge about a suspect linked to a criminal clan, while Laura and Giuseppe share moments of complicity that lighten the tension of the investigation.

In this moment of confrontation, Irene and Luca face the consequences of what happened, while within the group of students tension grows between some of them. Between misunderstandings, sense of responsibility and need for closeness, emotional conflicts and fragments of daily life alternate.

Gaetano notices that Camilla is more serene and she confides in him that Renzo, too, finally seems to have calmed down. However, the peace is shattered when Ventruti reaches the commissioner to get confirmation about the identity of the woman found dead. Devastated, the man lets all his pain emerge and reveals details that could prove crucial for the investigation.

A mysterious phone call casts Lojacono into shadow: a stranger from Agrigento hints at an unpaid mortgage and lets slip a veiled threat.
Meanwhile, Romano focuses all his anguish on little Giorgia. Between fear and hope, the doctors try to reassure him about the child's condition.

A song about pain and heartbreak serves as background to the students who receive news of maestro Marioni's absence, due to a minor accident. The suspension of orchestra rehearsals generates different reactions among the young people, between relief, expectations for an upcoming concert and reflections on shared work.

Anna and Camilla enter Quantunque's apartment to understand why he hasn't been to the restaurant anymore; the only suspicious element is a suitcase locked with a combination. Meanwhile, at home, Renzo appears more serene after talking with his mother-in-law and attempts a reconciliation by preparing dinner.