Once again, Caravaggio is criticized for using a woman considered to be a prostitute in a painting of the Virgin Mary. This time, there are consequences for Lena, too.

Ranuccio and Michele have a real duel. It's bloody and violent.

Tomassoni is dead and there is a death warrant out for Michele. Costanza and her son have to make some new plans, as not even Naples is safe for Michele.

Michele makes the trip to the island of Malta, where he meets the Grand Master of the Knights of Malta, hoping for protection. In Rome, his paintings are being removed from churches, since he is now considered to be a murderer.

On the island of Malta, Michele recognizes someone from his distant past to whom he expresses the wish to become one of the Knights of Malta.

Michele has almost finished his painting for the Knights of Malta and his protectors seem very pleased when they see it. They also have some important news for him.

Michele is learning how to use his sword like a true knight when he is challenged by a fellow knight. Things don't end well and Michele is once again facing arrest.

Michele has been abandoned at the bottom of the shaft, along with lots of rats. Will anyone save him?

De Ponte is still intent on finding Caravaggio to arrest him. Fortunately, the artist has people who want to protect him and is taken by boat to Siracusa, where a friend takes him in.

Michele is painting and doesn't want to stop, even to eat, until he has finished. He is also having nightmares. The Marquise pays an unusual visit.

Michele arrives in Messina. Filide pays a visit to a Cardinal she knows, to try to negotiate a pardon for Michele.

Michele is still in Sicily and is feeling justifiably paranoid. A painting he had done in secret is on display in a small church. But there are some criticisms and he doesn't react passively.

The ship arrives at the mainland and Cardinal Gonzaga instructs his men to escort Michele to land in a dinghy. The Cardinal will follow with the travel documents and paintings. Michele is a bit suspicious, but has no choice.

Michele receives some apologies and some help to search for the boat with his canvases. The Marquise is trying to reach him.

Caravaggio is in a bad way, and the fishermen agree on how to handle him. The Marquise is desperately trying to reach Porto Ercole to meet him.