Renzo, left without work, goes through a moment of deep frustration and is hurt when he discovers that Camilla tried to help him by turning to Gaetano. Between jealousy, pride and hurtful words, a domestic argument breaks out between the two that ends with Renzo's decision to go sleep on the studio couch.

A dive into memories of school years, between strikes, private schools, years of lead and friendships that left their mark. Between graduation grades, ski weeks, memorable quarrels and yellowed photos, the portrait of a group of very different girls takes shape, united by strong bonds, heated confrontations and that continuous need to prove something, especially to themselves.

Domenico postpones his appointment with Gloria, who is hurt and fears something is wrong. Matteo tries to make peace with his uncle to confess that he has invited some friends to dinner, while Sara finds herself dealing with a disappointment that puts her to an emotional test.

Gaetano and Camilla discuss their relationship difficulties, including jealousy and advice on how to communicate better. The conversation intertwines with investigative work when Camilla asks for more information regarding the recent murder.

Fabiola Gianotti here tells the story of how her passion for physics was born: from the influence of a great teacher and from reading Marie Curie's biography, to choosing physics as a fundamental discipline and arriving at CERN, experienced as an extraordinary place for scientific research.

Marioni interrupts a lesson by his colleague Guido and harshly confronts Nathan, ordering him to show up for rehearsals with the others. The tensions center around Sara, causing conflicts to explode in the group and bringing personal vulnerabilities to light.

Ottavia and Romano speak with Senatore who tells about his ambiguous relationship with Lara, described as an honest, reserved woman full of grace. After rejecting his advances, Lara decides to leave suddenly and when he is told that she was pregnant, the man appears genuinely surprised.

Camilla introduces a reflection on couple relationships drawing inspiration from literary examples, to analyze the theme of women who are socially and economically stronger than men. Meanwhile, Torre and Berardi conduct a neighborhood investigation that leads to gossip and everyday banality, between soap operas and moral judgments.

Fabiola Gianotti describes CERN as a place of encounter, growth and international cooperation; a young and multicultural environment where science is experienced in a democratic way. The archival images celebrate the original spirit of CERN: an extraordinary adventure.

The group gets together for an evening among friends, marked however by some absences. Between relationships that are ending and unexpected revelations, the group still tries to stay united. A final toast celebrates a friendship that endures, despite everything.

Mrs. Nubila retraces what she knows about Lara, the young woman welcomed with almost filial affection into her family. However, the fragile balance of her life is shattered by her husband's sudden return. Di Nardo and Lojacono reveal to her an aspect of Lara's story that the woman was unaware of.

Commissioner Berardi investigates the disappearance of Mrs. Torrielli and, during an inspection, interrogates the widower Ventruti. In an informal setting, over coffee, an important detail emerges: Flora's new address.

In the video Renzo Piano and Fabiola tell about CERN as a symbol of the cultural and scientific rebirth of the post-war period. Through personal memories and everyday dialogues, CERN emerges as a place of human and international encounter, founded on curiosity, peaceful collaboration and love for knowledge.

Through song, Matteo, rejected by Barbara, who chooses to remain just a friend, expresses his pain. Sofia's unconfessed feelings also emerge, as she loves Matteo in silence.

Between interrogations, conflicting leads and multiplying suspicions, secrets emerge linked to the victim and their private life. Meanwhile Romano faces the weight of his own guilt and the violence he committed but is called back to a sense of responsibility by the group.