This episode will take us to Umbria. We start with one of the most beautiful cities in the region, Assisi, a city that's practically synonymous with the Franciscan monastic order and its founder, Saint Francis.

Two geniuses left their indelible marks on civilization: Leonardo with the Last Supper and Michelangelo with his David.

We look at Leonardo's Last Supper from close up — the details, the symbolism — but also from the refectory floor, seeing how Leonardo's genius made the fresco part of the room itself.

This video focuses on one of the most famous artists of all time, Leonardo da Vinci. In particular, we start looking at one of his greatest masterpieces, the Last Supper.

The Republic of Siena ends in the 16th century and power goes to Florence, where we go next, to see some of the architectural wonders there.

Alberto Angela shows us a volume from 1554 that bears witness to one of the most dramatic moments in Sienese history. We then go on to the beautiful city of Pienza.

How could accounting books be so fascinating? The ones from the State Archives in Siena are veritable works of art and tell some interesting stories.

We have a look at two important medieval manuscripts in the State Archives. They are the original Constitution of the Republic of Siena. Alberto Angela gives us some fascinating facts concerning it that reaffirm how wise the rulers of that republic were.

The Siena Cathedral is large, but it was supposed to have become much, much bigger. Alberto Angela tells the fascinating story.

Alberto Angela explores the Piccolomini Altarpiece with sculptures by Michelangelo, and the beautiful frescoed Piccolomini Library within the walls of the Siena Cathedral

Alberto Angela focuses on one of the floor inlays depicting the story of Siena according to tradition. Siena shares a city symbol with Rome.

The Siena Cathedral is one of the most notable examples of Italian Romanesque-Gothic cathedrals, and is well worth a visit, for both the beauty of the exterior and the unique marble artwork on the interior.

Alberto Angela brings medieval Siena to life, with the help of some breathtaking aerial shots.

We are now in the heart of Italy: Tuscany. One of the most beautiful and important cities in Tuscany is Siena with its very particular piazza.

Alberto Angelo tells us the fascinating story of how trulli are built. Some of the most characteristic trulli can be found in Alberobello.