Eda discovered Margherita Hack on a TV show hosted by Piero Angela. This changed Eda's life. Margherita as a young scientist had a rough time in a profession where men were the important ones and had little regard for women.

Manzi's family is helping him get ready for the big evening, his first lesson on TV. Ida has gone to great lengths to get everything as perfect as possible. And even their neighbors want to see his debut.

Giulio takes Lele to an exhibit in order to have him meet the lady from the fax. Lele goes home only to find a new guest, not a human one.

Vittorio De Sica, along with other filmmakers and actors, does not want to be transferred to Venice, as has been mandated by the State. There, he would have to shoot propaganda movies for the Fascists. Luckily a Catholic film company wants to make a movie about a train of sick and deformed people on their way to seek miracles at the shrine of Our Lady of Loreto, a popular pilgrimage destination in the Marches region. The kind of train that carries pilgrims is called un treno bianco (a white train).

Camilla spends the afternoon at Dora's place, and they have a lot to talk about. Of course, Camilla loses track of the time.

At police headquarters, Ottavia discovers some surprising information about Ramaglia, the driver, so Lojacono and Aragona go back to see the Filangeri sisters, who seem as confused as ever. Palma reports to his boss, who is familiar with the Filangeri family.

Luigi has another conversation with Zamagna, but isn't sure if it is really him. Luigi is not out of the woods yet.

A car problem allows us to meet Eda Gjergo, a young astrophysicist, who will in turn lead us to meet Margherita Hack, the subject of this episode about women luminaries. Hack was a famous scientist, communicator, and activist.

Moscati tries to calm the crowd of people and help them understand that it isn't necessary to burn all their household belongings, and that cholera is transmitted through their drinking water. He promises to help treat them as Elena watches the scene from afar.

Manzi is interviewed by the program team at RAI headquarters. They worry that he will be out of control with the whole world watching, but they appreciate how good his audition was. Meanwhile, Ricotta seems to have found a job, and once again, his studies at the reformatory have proved to be surprisingly valuable.

Ciccio is in bed pretending to be sick when his grandparents show up. They have a gift for him. At the clinic, a woman shows up and is examined by Mariano, but there's a problem.

When the Americans bombed Rome in 1943, Maria was shooting a film in the San Lorenzo area, right where the freight yards were, the target of the bombing. Vittorio, on the other side of town, rushed to the site. Life would soon become extremely complicated and dangerous for those in the film industry.

Camilla finds herself with her pants soaked in milk that has leaked from the container in her bag. The woman she is talking to her invites her home to change. While she is there, Gaetano calls her back.

The two women tell conflicting stories about the murder and it is frustrating for the officers. De Nardo has some uncomfortable conversations at home with her parents.

Pimpa wakes up to a strange sight in her living room. Once she figures out the problem, she sets out to help resolve it.